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Article

Three gonadotropin-releasing hormone genes in one organism suggest novel roles for an ancient peptide.

29 Aug 1995

Abstract excerpt

Gonadotropin-releasing hormone (GnRH) is known and named for its essential role in vertebrate reproduction. Release of this decapeptide from neurons in the hypothalamus controls pituitary gonadotropin levels which, in turn, regulate gonadal state. The importance of GnRH is underscored by its widespread expression and conservation across vertebrate taxa: five amino acids are invariant in all nine known forms,...

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Identifiers

PMID: 7667296
DOI: 10.1073/pnas.92.18.8363

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