Article
Inhibitory effect of stromal cell derived factor-1 on the replication of divergent strains of feline immunodeficiency virus in a feline T-lymphoid cell line.
Veterinary immunology and immunopathology - 23 May 2000
Endo Y, Goto Y, Nishimura Y, Mizuno T, Watari T, Hasegawa A, Hohdatsu T, Koyama H, Tsujimoto H
Abstract excerpt
The effect of a CXC-chemokine, stromal cell derived factor-1 (SDF-1), on the replication of divergent strains of feline immunodeficiency virus (FIV) was examined in order to identify the mechanism of cell entry of FIV. A chemotaxis assay, using a modified Boyden chamber method, confirmed the biological activity of recombinant human (rh) SDF-1 for a feline T-lymphoid cell line (Kumi-1). The viral replication of...
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