Article
Localization of the locus responsible for Chediak-Higashi syndrome in cattle to bovine chromosome 28.
Animal genetics - 1 Apr 2000
Kunieda T, Ide H, Nakagiri M, Yoneda K, Konfortov B, Ogawa H
Abstract excerpt
Chediak-Higashi syndrome in Japanese black cattle is a hereditary disease with prolonged bleeding time and partial albinism. In the present study, we mapped the locus responsible for the disease (CHS) by linkage analysis using microsatellite genotypes of paternal half-sib pedigrees obtained from commercial herds. Analysis revealed significant linkage between the CHS locus and marker loci on the proximal end of...
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