Article
Influence of viral load and alanine aminotransferase on viral genetic heterogeneity in patients with chronic hepatitis C virus infection.
Intervirology - 1 Jan 2000
Bozdayi A M, Uzunalimoglu O, Aslan N, Bozkaya H, Türkyilmaz A R, Kayhan B, Sahin T, Sivri B, Uygun A, Altiok A, Cetinkaya H, Karayalçin S, Yurdaydin C
Abstract excerpt
BACKGROUND/AIM: Hepatitis C virus (HCV) populations in vivo consist of genetically different heterogeneous mixtures defined as 'quasispecies', which vary in the hypervariable region 1 (HVR1) mostly. To further address the role of quasispecies diversity in hepatitis C infection, this study aimed to evaluate the influence of ALT, viral load and genotypes on quasispecies heterogeneity in patients with HCV infection....
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