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Article

Ring formation drives invagination of the vulva in Caenorhabditis elegans: Ras, cell fusion, and cell migration determine structural fates.

Developmental biology - 1 May 2000

Shemer G, Kishore R, Podbilewicz B

Abstract excerpt

Directed cell rearrangements occur during gastrulation, neurulation, and organ formation. Despite the identification of developmental processes in which invagination is a critical component of pattern formation, little is known regarding the underlying cellular and molecular details. Caenorhabditis elegans vulval epithelial cells undergo morphological changes that generate an invagination through the formation of...

Topics

Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Cell Fusion
Cell Lineage
Cell Movement
Female
Fluorescent Antibody Technique
Genitalia, Female
Helminth Proteins
Microscopy, Confocal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Morphogenesis

Mutation

Signal Transduction

ras Proteins

Source

Identifiers

PMID: 10772804
DOI: 10.1006/dbio.2000.9657

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-10772804-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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