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Article

Exogenous mutant p53 DNA enhanced cisplatin-induced apoptosis in TSGH-8301 human bladder cancer cells.

Anticancer research - 1 Jan 2000

Chang F L, Ling Y F, Lai M D

Abstract excerpt

BACKGROUND: The influence of tumor suppressor gene p53 on the apoptosis of bladder cancer cells is not completely understood. In this study, the requirement for p53 in the cisplatin-induced apoptosis of human bladder cancer cells TSGH-8301 was investigated. MATERIALS AND METHODS: TSGH-8301 cells, which contain endogenous wild type p53 genes, were transfected with expression vectors containing p53 cDNA mutated at...

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PMID: 10769676

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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