Article
Polymorphism of alpha 1-antitrypsin in North American species of Canis.
The Journal of heredity - 1 Jan 2000
Federoff N E, Kueppers F
Abstract excerpt
alpha 1-Antitrypsin (A1AT) is a major protease inhibitor present in all mammalian sera that have thus far been investigated. A1AT is also highly polymorphic and is therefore a useful genetic marker. Previously reported A1AT polymorphism in domestic dogs consisted of two alleles designated as PiM and PiS which exhibited frequencies of 0.72 and 0.28, respectively, in a group of randomly collected mongrel dogs....
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