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Article

Smoking and chronic obstructive pulmonary disease.

Clinics in chest medicine - 1 Mar 2000

Sethi J M, Rochester C L

Abstract excerpt

Smoking is overwhelmingly the major cause of chronic bronchitis and emphysema worldwide. Additional risk factors for developing COPD are presented, along with the variables that govern cigarette smoke deposition in the lung. Major paradigms for the pathogenesis of COPD, including the protease-antiprotease and oxidant-antioxidant theories are described, and evidence for impaired reparative mechanisms in the...

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Identifiers

PMID: 10763090
DOI: 10.1016/s0272-5231(05)70008-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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