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Article

Mutations in zinc-binding domains of p53 as a prognostic marker of esophageal-cancer patients.

Japanese journal of cancer research : Gann - 1 Feb 2000

Kihara C, Seki T, Furukawa Y, Yamana H, Kimura Y, van Schaardenburgh P, Hirata K, Nakamura Y

Abstract excerpt

Some investigators have suggested that mutations of the p53 gene may be molecular markers for poor prognosis of cancer patients, although others have reported conflicting results. We examined esophageal cancers from 138 patients to investigate whether mutational status of p53 could be correlated either with prognosis or with response to chemotherapy or radiation. We detected p53 mutations in the tumors of 78...

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Identifiers

PMID: 10761706
DOI: 10.1111/j.1349-7006.2000.tb00931.x
PMCID: PMC5926332

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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