Article
[Prognostic factors for esophageal cancer--from the viewpoint of molecular biology].
Gan to kagaku ryoho. Cancer & chemotherapy - 1 Jul 1996
Shimada Y, Imamura M
Abstract excerpt
The prognostic factors for esophageal cancer from the viewpoint of molecular biology are reviewed. Among several oncogenes and suppressor genes erbB, int2/hst1/Cyclin D1 and MDM2 gene amplifications are significant prognostic factors for esophageal cancer. The value of p53 mutation, and expression of matrix metalloproteinase (MMPs) in the prediction of patients' survival are controversial, so further research is...
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