Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ancient origin of the null allele se(428) of the human ABO-secretor locus (FUT2).

Journal of molecular evolution - 1 Mar 2000

Koda Y, Tachida H, Soejima M, Takenaka O, Kimura H

Abstract excerpt

In human populations, a null allele having several nucleotide differences from the wild-type allele is segregating at the FUT2 locus (the ABO-Secretor locus) encoding alpha(1,2)fucosyltransferase. To estimate the age of the most recent common ancestor (MRCA) of these two alleles, we sequenced FUT2 homologues from chimpanzee, gorilla, orangutan, and green monkey. Since we did not detect acceleration or any...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ABO Blood-Group System
Share to Base Sequence
Share to COS Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Evolution, Molecular

Share to Fucosyltransferases

Share to Galactoside 2-alpha-L-fucosyltransferase

Share to Genetic Heterogeneity

Source

Identifiers

PMID: 10754067
DOI: 10.1007/s002399910028

Genes

FUT2
ABO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ancient origin of the null allele se(428) of the human ABO-secretor locus (FUT2).PMID 10754067Read ↗

DNA sequence variation of the human ABO-secretor locus ( FUT2) in New Guinean populations: possible early human migration from Africa.Semantic proximity Read ↗

A natural history of FUT2 polymorphism in humans.Semantic proximity Read ↗

Polymorphism of the human ABO-Secretor locus (FUT2) in four populations in Asia: indication of distinct Asian subpopulations.Semantic proximity Read ↗

Polymorphism of the human ABO‐Secretor locus (<i>FUT2</i>) in four populations in Asia: indication of distinct Asian subpopulationsSemantic proximity Read ↗

Infection-associated FUT2 (Fucosyltransferase 2) genetic variation and impact on functionality assessed by in vivo studies.Semantic proximity Read ↗

Survey and Characterization of Nonfunctional Alleles of FUT2 in a DatabaseSemantic proximity Read ↗

Survey and characterization of nonfunctional alleles of FUT2 in a database.Semantic proximity Read ↗

Contrasting patterns of polymorphisms at the ABO-secretor gene (FUT2) and plasma alpha(1,3)fucosyltransferase gene (FUT6) in human populations.Semantic proximity Read ↗

Systematic sequence analysis of the human fucosyltransferase 2 (FUT2) gene identifies novel sequence variations and alleles.Semantic proximity Read ↗

Two distinct Alu-mediated deletions of the human ABO-secretor (FUT2) locus in Samoan and Bangladeshi populations.Semantic proximity Read ↗

Genetic variation of FUT2 in Ovambos, Turks, and Mongolians.Semantic proximity Read ↗

Human pseudogenes of the ABO family show a complex evolutionary dynamics and loss of function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.