Bicoid-independent formation of thoracic segments in Drosophila.

doi:10.1126/science.287.5462.2476

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Article

Bicoid-independent formation of thoracic segments in Drosophila.

Science (New York, N.Y.) - 31 Mar 2000

Wimmer E A, Carleton A, Harjes P, Turner T, Desplan C

Abstract excerpt

The maternal determinant Bicoid (Bcd) represents the paradigm of a morphogen that provides positional information for pattern formation. However, as bicoid seems to be a recently acquired gene in flies, the question was raised as to how embryonic patterning is achieved in organisms with more ancestral modes of development. Because the phylogenetically conserved Hunchback (Hb) protein had previously been shown to...

Topics

Animals
Body Patterning
DNA-Binding Proteins
Drosophila
Drosophila Proteins
Embryonic Development
Female
Gene Expression Regulation, Developmental
Genes, Insect
Homeodomain Proteins
Insect Proteins
Male
Mutation
Phenotype
Promoter Regions, Genetic
Thorax
Trans-Activators
Transcription Factors

Source

Open in PubMed

Identifiers

PMID: 10741965
DOI: 10.1126/science.287.5462.2476

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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