Article
Establishment and epitope analysis of allo-specific cytotoxic T lymphocytes at a tumor site recognizing a spouse's HLA-A0206 molecule.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Mar 2000
Seki N, Yamada A, Suefuji Y, Mine T, Tanaka S, Gomi S Y, Kawagoe N, Koufuji K, Itoh K
Abstract excerpt
PROBLEM: The molecular basis of allo-reactivity in reproductive immunity has not been fully clarified. METHOD OF STUDY: Cytotoxic T lymphocytes (CTLs) were established from tumor-infiltrating lymphocytes (TILs). The allo-reactivity of the CTLs against various tumor cell lines or human leukocyte antigen (HLA)-A allele-transfected COS-7 cells was measured by 51Cr-release or interferon-gamma production assay....
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