Direct Extracellular Contact between Integrin α3β1 and TM4SF Protein CD151

Abstract excerpt

Previously we established that the alpha(3)beta(1) integrin shows stable, specific, and stoichiometric association with the TM4SF (tetraspannin) protein CD151. Here we used a membrane impermeable cross-linking agent to show a direct association between extracellular domains of alpha(3)beta(1) and CD151. The alpha(3)beta(1)-CD151 association site was then mapped using chimeric alpha(6)/alpha(3) integrins and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biochemical and Structural Characterization
• Share to Cell Adhesion Molecules Research
• Share to Signaling Pathways in Disease