Article
Androgen insensitivity.
American journal of medical genetics - 29 Dec 1999
Gottlieb B, Pinsky L, Beitel L K, Trifiro M
Abstract excerpt
The androgen receptor (AR) protein regulates transcription of certain genes. Usually, this activity depends upon a central DNA-binding domain that permits the binding of androgen-AR complexes to regulatory DNA sequences near or in a target gene. The AR also has a C-terminal androgen-binding domain (ABD) and an N-terminal modulatory domain. These domains interact among themselves and with coregulatory, nonreceptor...
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