Article
Androgen insensitivity syndrome: a review.
Archives of endocrinology and metabolism - 1 Jan 2000
Batista Rafael Loch, Costa Elaine M Frade, Rodrigues Andresa de Santi, Gomes Nathalia Lisboa, Faria José Antonio, Nishi Mirian Y, Arnhold Ivo Jorge Prado, Domenice Sorahia, Mendonca Berenice Bilharinho de
Abstract excerpt
Androgenic insensitivity syndrome is the most common cause of disorders of sexual differentiation in 46,XY individuals. It results from alterations in the androgen receptor gene, leading to a frame of hormonal resistance, which may present clinically under 3 phenotypes: complete (CAIS), partial (PAIS) or mild (MAIS). The androgen receptor gene has 8 exons and 3 domains, and allelic variants in this gene occur in...
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