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Human cystathionine γ-lyase: developmental and in vitro expression of two isoforms

27 Mar 2000

Abstract excerpt

Cystathionine gamma-lyase (CGL) is the last enzyme of the trans-sulphuration pathway, which converts methionine into cysteine. To study the possible differences in enzymic activity of the two human cystathionine gamma-lyase isoforms characterized earlier, these were separately expressed in human kidney embryonic 293T cells. Furthermore, developmental changes in the expression of the two mRNA forms as well as the...

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PMID: 10727430
DOI: 10.1042/bj3470291

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