Article
Molecular epidemiologic approaches to urinary tract infection gene discovery in uropathogenic Escherichia coli.
Infection and immunity - 1 Apr 2000
Zhang L, Foxman B, Manning S D, Tallman P, Marrs C F
Abstract excerpt
Urinary tract infection (UTI) is one of the most frequently acquired bacterial infections. The vast majority of UTIs are caused by a large, genetically heterogeneous group of Escherichia coli. This genetic diversity has hampered identification of UTI-related genes. A three-step experimental strategy was used to identify genes potentially involved in E. coli UTI transmission or virulence: epidemiologic pairing of...
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