Article
Gene-environment interactions in human lung cancer.
Toxicology letters - 15 Mar 2000
Haugen A, Ryberg D, Mollerup S, Zienolddiny S, Skaug V, Svendsrud D H
Abstract excerpt
Gene-environment interactions are thought to be critical for several diseases such as cancer, diabetes, heart disease and asthma. Cancer is a result of multiple gene-environment interactions occurring over several decades. During tumor development the cell accumulates multiple genetic changes, which generate the transformed phenotype, i.e. a cell with increased genetic instability. Lung cancer is a useful model...
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