Article
HLA-DR and HLA-DQ gene typing of infertile women possessing sperm-immobilizing antibody.
Journal of reproductive immunology - 1 Feb 2000
Tsuji Y, Mitsuo M, Yasunami R, Sakata K, Shibahara H, Koyama K
Abstract excerpt
Thirty-eight infertile women, possessing sperm-immobilizing antibody (SIA), were examined for their HLA-DR and -DQ types using DNA obtained from peripheral blood cells. The typing of HLA-DR and DQ was performed by polymerase chain reaction sequence specific oligonucleotide probes (PCR-SSOP) and PCR-restriction fragment length polymorphism (RFLP), respectively. In comparison to the normal Japanese population, the...
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