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Article

Abnormal timing in the prenatal ossification of vertebral column and hand in Crouzon syndrome.

American journal of medical genetics - 28 Feb 2000

Kjaer I, Hansen B F, Kjaer K W, Skovby F

Abstract excerpt

We report on a radiographically examined fetus (gestational age 13 weeks) with Crouzon syndrome caused by a mutation in the gene encoding the fibroblast growth factor 2 (FGFR2). We found an approximately 2-week delay in vertebral body and hand ossification with normal vertebral arch ossification, suggesting that regionally delayed skeletal maturation might be a manifestation of FGFR2 mutation syndromes. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Fibroblast Growth Factor, Type 2

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Source

Identifiers

PMID: 10706360
DOI: 10.1002/(sici)1096-8628(20000228)90:5<386::aid-ajmg8>3.0.co;2-m

Genes

FGFR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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