Article
Identification of the novel allele HLA-B*1545: assessment of alloreactivity in case of mismatch with other B*15 alleles.
Tissue antigens - 1 Jan 2000
Elsner H A, Blasczyk R
Abstract excerpt
The novel allele HLA-B*1545, which has been serologically typed as B62, was identified in a male Caucasian. In the sequence analysis the new allele differs from B*1507 by nucleotide 419 which is located in exon 3. Its structure suggests that it may have originated by a point mutation or by gene conversion with a variety of HLA-B alleles. At the protein level, the nucleotide substitution results in an amino add...
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