Article
A new HLA-Cw allele (Cw*1510), identified in a French Caucasian individual.
Tissue antigens - 1 Aug 2001
Tamouza R, Schaeffer V, Marzais F, Poirier J C, Fortier C, Ramasawmy R, Sghiri R, Krishnamoorthy R, Toubert A, Charron D
Abstract excerpt
A novel HLA-Cw*15 allele, Cw*1510, found in a French Caucasian bone marrow recipient is described. Nucleotide sequence of the new variant is identical to the common Cw*15021 DNA sequences except nucleotides at positions 32 and 61 of exon 2. While the first difference is silent, the second cause substitution of an Histidine by an Arginine at amino acid position 21 of the alpha1 heavy chain domain.
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