Article
A novel HLA-Cw*07 variant, HLA-Cw*0760, identified by sequence-based typing in a bone marrow donor.
Tissue antigens - 1 Aug 2009
Martínez-Martínez L, González-Santesteban C, Agustí-Martí M, Pérez-Ranz E, de la Calle-Martín O
Abstract excerpt
We report the identification of the novel allele HLA-Cw*0760 that was found during confirmatory high-resolution sequence-based typing of a bone marrow donor. The Cw*0760 allele has two nucleotide changes from Cw*070101 at positions 341 and 343 in exon 2, resulting in two amino acid changes from Asp to Ala (codon 90: GAC-->GCC) and Gly to Arg (codon 91: GGG-->AGG).
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