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Article

Human three-dimensional fibroblast cultures express angiogenic activity.

Journal of cellular physiology - 1 Apr 2000

Pinney E, Liu K, Sheeman B, Mansbridge J

Abstract excerpt

Human neonatal fibroblasts were cultured on a lactate-glycollate copolymer scaffold for 12-16 days to form a three-dimensional dermal equivalent tissue. The cellular content of vascular endothelial growth factor (VEGF) mRNA in these three-dimensional cultures was 22-fold greater than that observed in the same fibroblasts grown as monolayers. No induction was shown by hepatocyte growth factor (HGF) or angiopoietin...

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Source

Identifiers

PMID: 10699968
DOI: 10.1002/(SICI)1097-4652(200004)183:1<74::AID-JCP9>3.0.CO;2-G

Genes

HGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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