Functional Heterodimerization of Prolactin and Growth Hormone Receptors by Ovine Placental Lactogen

Abstract excerpt

Although homo- or heterodimerization are common mechanisms for activation of cytokine receptors, cross-talk between two distinct receptors in this superfamily has been never shown. Here we show a physiologically relevant example indicating that such an interaction does occurs, thus raising the hypothesis that heterodimerization between distinct cytokine receptors may be a novel mechanism contributing to the...

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