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Article

Efficient studies of long-distance Bmp5 gene regulation using bacterial artificial chromosomes.

Proceedings of the National Academy of Sciences of the United States of America - 15 Feb 2000

DiLeone R J, Marcus G A, Johnson M D, Kingsley D M

Abstract excerpt

The regulatory regions surrounding many genes may be large and difficult to study using standard transgenic approaches. Here we describe the use of bacterial artificial chromosome clones to rapidly survey hundreds of kilobases of DNA for potential regulatory sequences surrounding the mouse bone morphogenetic protein-5 (Bmp5) gene. Simple coinjection of large insert clones with lacZ reporter constructs...

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Share to Bone Morphogenetic Proteins
Share to DNA, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

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Share to Regulatory Sequences, Nucleic Acid

Source

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Identifiers

PMID: 10677507
DOI: 10.1073/pnas.97.4.1612
PMCID: PMC26483

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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