Article
Secretor polymorphism and human immunodeficiency virus infection in Senegalese women.
The Journal of infectious diseases - 1 Feb 2000
Ali S, Niang M A, N'doye I, Critchlow C W, Hawes S E, Hill A V, Kiviat N B
Abstract excerpt
The FUT2 gene encodes the enzyme alpha (1,2) fucosyltransferase, which determines expression of blood-group antigens on mucosal epithelial cell surfaces and in secretions. Homozygotes for a specific stop mutation in FUT2 (nonsecretors) cannot produce this enzyme and thus are unable to express blo...
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