Article
Post mortem molecularly defined familial hypercholesterolemia and sudden cardiac death of young men.
Forensic science international - 6 Dec 1999
Vuorio A F, Kontula K, Turtola H, Sajantila A
Abstract excerpt
Familial hypercholesterolemia (FH) is among the most common single-gene diseases and is due to mutations of the low-density lipoprotein (LDL) receptor gene. In heterozygous FH, serum LDL-cholesterol level is elevated two- to threefold compared to unaffected individuals, men in particular are prone to premature atherosclerosis and early cardiac deaths. However, very little data are available concerning the...
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