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Article

MLV-derived retroviral vectors selective for CD4-expressing cells and resistant to neutralization by sera from HIV-infected patients.

Virology - 15 Feb 2000

Stitz J, Steidl S, Merget-Millitzer H, König R, Müller P, Nocken F, Engelstädter M, Bobkova M, Schmitt I, Kurth R, Buchholz C J, Cichutek K

Abstract excerpt

Retroviral vectors derived from amphotropic murine leukemia viruses (MLV) mediate gene transfer into almost all human cells and are thus not suitable for in vivo applications in gene therapy in which cell-specific gene delivery is required. We and others recently reported the generation of MLV-derived vectors pseudotyped by variants of the envelope glycoproteins (Env) of human immunodeficiency virus type 1...

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Share to DNA, Recombinant
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia Virus, Murine

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Source

Identifiers

PMID: 10662618
DOI: 10.1006/viro.1999.0121

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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