Signaling Activities of Gammaherpesvirus Membrane Proteins

Abstract excerpt

Members of the Herpesviridae family have large doublestranded DNA genomes and replicate in the nucleus of the host cell. Based on genomic organization and biological characteristics, herpesviruses are classified into three subfamilies: alpha, beta, and gamma (Fig. 1A). The gammaherpesviruses replicate and persist in lymphoid cells, but some are capable of undergoing lytic replication in epithelial or fibroblast...

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