Article
A new disorder of hyaluronan metabolism associated with generalized folding and thickening of the skin.
The Journal of pediatrics - 1 Jan 2000
Ramsden C A, Bankier A, Brown T J, Cowen P S, Frost G I, McCallum D D, Studdert V P, Fraser J R
Abstract excerpt
OBJECTIVE: To describe and characterize a new disorder of hyaluronan metabolism associated with marked abnormalities of cutaneous tissue and to determine whether a relationship with a phenotypically similar disorder in the shar-pei dog exists. METHODS: Biopsy specimens of the skin of a child with extreme cutaneous thickening and folding were examined by light and electron microscopy. The concentration of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.