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Article

Hereditary cutaneous mucinosis in shar pei dogs is associated with increased hyaluronan synthase-2 mRNA transcription by cultured dermal fibroblasts.

Veterinary dermatology - 1 Oct 2009

Zanna Giordana, Docampo María J, Fondevila Dolors, Bardagí Mar, Bassols Anna, Ferrer Lluís

Abstract excerpt

Shar pei dogs are known for the distinctive feature of thick, wrinkled skin as a consequence of high dermal mucin content. Excessive dermal deposition of mucinous substance leading to severe skin folding, and/or to the more severe vesicular form characterized by dermal vesicles or bullae, is highly prevalent in this breed and is known as idiopathic mucinosis. Hyaluronic acid (HA) is the main component that...

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Source

Identifiers

PMID: 20178474
DOI: 10.1111/j.1365-3164.2009.00799.x

Genes

HAS2
HAS1
HAS3
HYAL1
HYAL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Hereditary cutaneous mucinosis in shar pei dogs is associated with increased hyaluronan synthase-2 mRNA transcription by cultured dermal fibroblasts.PMID 20178474Read ↗

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