Article
Genotype/phenotype correlation of multiple endocrine neoplasia type 1 gene mutations in sporadic gastrinomas.
The Journal of clinical endocrinology and metabolism - 1 Jan 2000
Goebel S U, Heppner C, Burns A L, Marx S J, Spiegel A M, Zhuang Z, Lubensky I A, Gibril F, Jensen R T, Serrano J
Abstract excerpt
Multiple endocrine neoplasia type 1 (MEN1) gene mutations are reported in some gastrinomas occurring in patients without MEN1 as well as in some other pancreatic endocrine tumors (PETs). In some inherited syndromes phenotype-genotype correlations exist for disease severity, location, or other manifestations. The purpose of the present study was to correlate mutations of the MEN1 gene in a large cohort of patients...
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