Article
[L-myc and GSTM1 polymorphism in cerebral glioma].
Voprosy onkologii - 1 Jan 1999
Kondrat'eva T V, Imianitov E N, Togo A V, Zaĭtseva O A, Iatsuk O S, Bersnev V P, Khanson K P
Abstract excerpt
L-MYC and GSTMI polymorphisms were studied in glioma patients. L-MYC allele frequency in patients (L: 61/114 (54%); S: 53/114 (46%)) and controls (L: 108/204 (53%); S: 96/204 (47%)) was identical. S allele was associated with certain unfavourable clinical features of the disease. In particular, its frequency was 26/42 (62%) in relapse vs. 26/68 (38%) in relapse-free disease (p < 0.05). GSTMI "null" genotype was...
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