Dynamic movement of the ParA-like Soj protein of B. subtilis and its dual role in nucleoid organization and developmental regulation.

doi:10.1016/s1097-2765(00)80378-0

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Article

Dynamic movement of the ParA-like Soj protein of B. subtilis and its dual role in nucleoid organization and developmental regulation.

Molecular cell - 1 Nov 1999

Marston A L, Errington J

Abstract excerpt

The Spo0J and Soj proteins of B. subtilis belong to a widespread family of bacterial proteins required for accurate segregation of plasmids and chromosomes. Spo0J binds to several sites around the oriC region of the chromosome, which are organized into compact foci that may play a centromere-like role in active chromosome segregation. We now show that Soj has a role in organization or compaction of Spo0J-oriC...

Topics

Bacillus subtilis
Bacterial Proteins
Biological Transport
Cell Division
Cell Polarity
Centromere
Chromosomes, Bacterial
Cytoskeletal Proteins
DNA, Bacterial
Gene Expression Regulation, Bacterial
Microscopy, Fluorescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Nalidixic Acid

Recombinant Fusion Proteins

Replication Origin

Sigma Factor

Time Factors

Transcription Factors

Source

Open in PubMed

Identifiers

PMID: 10619015
DOI: 10.1016/s1097-2765(00)80378-0

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Dynamic movement of the ParA-like Soj protein of B. subtilis and its dual role in nucleoid organization and developmental regulation.PMID 10619015Read ↗

Genetic analysis of the chromosome segregation protein Spo0J of Bacillus subtilis: evidence for separate domains involved in DNA binding and interactions with Soj protein.Semantic proximity Read ↗

Control of development by altered localization of a transcription factor in B. subtilis.Semantic proximity Read ↗

The chromosome partitioning proteins Soj (ParA) and Spo0J (ParB) contribute to accurate chromosome partitioning, separation of replicated sister origins, and regulation of replication initiation in Bacillus subtilis.Semantic proximity Read ↗

Spo0J regulates the oligomeric state of Soj to trigger its switch from an activator to an inhibitor of DNA replication initiation.Semantic proximity Read ↗

Complex polar machinery required for proper chromosome segregation in vegetative and sporulating cells of Bacillus subtilis.Semantic proximity Read ↗

Cell division protein DivIB influences the Spo0J/Soj system of chromosome segregation in Bacillus subtilis.Semantic proximity Read ↗

Soj (ParA) DNA binding is mediated by conserved arginines and is essential for plasmid segregation.Semantic proximity Read ↗

Whole-genome analysis of the chromosome partitioning and sporulation protein Spo0J (ParB) reveals spreading and origin-distal sites on the Bacillus subtilis chromosome.Semantic proximity Read ↗

Bacterial DNA segregation by dynamic SopA polymers.Semantic proximity Read ↗

Stochastic model for Soj relocation dynamics in Bacillus subtilis.Semantic proximity Read ↗

A role for division-site-selection protein MinD in regulation of internucleoid jumping of Soj (ParA) protein in Bacillus subtilis.Semantic proximity Read ↗

The bacterial chromosome segregation protein Spo0J spreads along DNA from parS nucleation sites.Semantic proximity Read ↗

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