Article
The four-jointed gene is required in the Drosophila eye for ommatidial polarity specification.
Current biology : CB - 2 Dec 1999
Zeidler M P, Perrimon N, Strutt D I
Abstract excerpt
BACKGROUND: The Drosophila eye is composed of about 800 ommatidia, each of which becomes dorsoventrally polarised in a process requiring signalling through the Notch, JAK/STAT and Wingless pathways. These three pathways are thought to act by setting up a gradient of a signalling molecule (or molecules) often referred to as the 'second signal'. Thus far, no candidate for a second signal has been identified....
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