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Article

Phosphorylation of bicoid on MAP-kinase sites: contribution to its interaction with the torso pathway.

Development (Cambridge, England) - 1 Jan 2000

Janody F, Sturny R, Catala F, Desplan C, Dostatni N

Abstract excerpt

The Torso signal transduction pathway exhibits two opposite effects on the activity of the Bicoid (Bcd) morphogen: (i) Bcd function is repressed by Torso (Tor) at the anterior pole of the embryo leading to a retraction of the expression of many Bcd targets from the most anterior region of the embryo, where the Tor tyrosine kinase receptor is activated, and (ii) Bcd function is strengthened by Tor in a broader...

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Identifiers

PMID: 10603346
DOI: 10.1242/dev.127.2.279

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 11 closest

Phosphorylation of bicoid on MAP-kinase sites: contribution to its interaction with the torso pathway.PMID 10603346Read ↗

The torso receptor localizes as well as transduces the spatial signal specifying terminal body pattern in Drosophila.Semantic proximity Read ↗

High bicoid levels render the terminal system dispensable for Drosophila head development.Semantic proximity Read ↗

Dissecting the mechanism of torso receptor activation.Semantic proximity Read ↗

Spatially distinct downregulation of Capicua repression and tailless activation by the Torso RTK pathway in the Drosophila embryo.Semantic proximity Read ↗

torso-like encodes the localized determinant of Drosophila terminal pattern formation.Semantic proximity Read ↗

The orthodenticle gene is regulated by bicoid and torso and specifies Drosophila head development.Semantic proximity Read ↗

Localized requirement for torso-like expression in follicle cells for development of terminal anlagen of the Drosophila embryo.Semantic proximity Read ↗

Torso, a receptor tyrosine kinase required for embryonic pattern formation, shares substrates with the sevenless and EGF-R pathways in Drosophila.Semantic proximity Read ↗

Terminal pattern elements in Drosophila embryo induced by the torso-like protein.Semantic proximity Read ↗

Zygotic genes that mediate torso receptor tyrosine kinase functions in the Drosophila melanogaster embryo.Semantic proximity Read ↗

Synergistic activities of multiple phosphotyrosine residues mediate full signaling from the Drosophila Torso receptor tyrosine kinase.Semantic proximity Read ↗

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