Article
Roles of FGFR2 and twist in human craniosynostosis: insights from genetic mutations in cranial osteoblasts.
Frontiers of oral biology - 1 Jan 2008
Marie Pierre J, Kaabeche Karim, Guenou Hind
Abstract excerpt
Recent advances in molecular genetics have led to a better understanding of the role of specific genes such as fibroblast growth factor receptor (FGFR) and Twist in cranial bone formation. Specifically, the analysis of osteoblast abnormalities induced by FGFR2 and Twist genetic mutations inducing craniosynostosis in humans has provided some insights into the role of these genes in the premature cranial suture...
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