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Article

Citalopram: an interaction study with clomipramine in a patient heterozygous for CYP2D6 genotype.

Pharmacopsychiatry - 1 Nov 1999

Haffen E, Vandel P, Broly F, Vandel S, Sechter D, Bizouard P, Bechtel P R

Abstract excerpt

A pharmacokinetic interaction between the selective serotonin reuptake inhibitor citalopram and a tricyclic antidepressant, clomipramine, was noted in a patient treated for major depression and obsessive-compulsive disorder. After the addition of citalopram, a desmethylclomipramine plasma level increase and an 8-hydroacy-desmethylclomipramine plasma level decrease were observed. The CYP2D6 phenotype, determined...

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Source

Identifiers

PMID: 10599932
DOI: 10.1055/s-1999-7960

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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