Article
Association of ACE and FACTOR VII gene variability with the risk of coronary heart disease in north Indian population.
Molecular and cellular biochemistry - 1 Aug 2010
Sobti R C, Maithil Nishi, Thakur Hitender, Sharma Yashpaul, Talwar K K
Abstract excerpt
The angiotensin converting enzyme (ACE) is a key factor in the production of angiotensin II and in the degradation of bradykinin. Chronic exposure to high levels of circulating and tissue ACE predispose to vascular wall thickening and atherosclerosis. Factor VII (FACTOR VII) is the first enzyme in the extrinsic pathway of the blood coagulation system and plays a key role in hemostasis; it also contributes to the...
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