Article
Searching for alcoholism susceptibility genes using Markov chain Monte Carlo methods.
Genetic epidemiology - 1 Jan 1999
Leal S M, Heath S C
Abstract excerpt
Markov chain Monte Carlo (MCMC) methods offer a rapid parametric approach that can test for linkage throughout the entire genome. It has an advantage similar to nonparametric methods in that the model does not have to be completely specified a priori. However, unlike nonparametric methods, there are no limitations on pedigree size and MCMC methods can also handle relatively complex pedigree structures. In...
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