Bronchodilator responsiveness and serum total IgE levels in families of probands with severe early-onset COPD.

doi:10.1183/09031936.99.14510099

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Bronchodilator responsiveness and serum total IgE levels in families of probands with severe early-onset COPD.

The European respiratory journal - 1 Nov 1999

Celedon J C, Speizer F E, Drazen J M, Weiss S T, Campbell E J, Carey V J, Reilly J J, Ginns L, Silverman E K

Abstract excerpt

Bronchodilator responsiveness has been associated with a subsequent accelerated decline in forced expiratory volume in one second (FEV1). Therefore, bronchodilator responsiveness and total serum immunoglobulin E(IgE) levels were assessed in 184 adult first-degree relatives of probands with severe early-onset chronic obstructive pulmonary disease (COPD) and a control group. Greater bronchodilator responsiveness...

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