Article
Hierarchy in the expression of the locus of enterocyte effacement genes of enteropathogenic Escherichia coli.
Molecular microbiology - 1 Dec 1999
Friedberg D, Umanski T, Fang Y, Rosenshine I
Abstract excerpt
Enteropathogenic Escherichia coli (EPEC) elicit changes in host cell morphology and cause actin rearrangement, a phenotype that has commonly been referred to as attaching/effacing (AE) lesions. The ability of EPEC to induce AE lesions is dependent upon a type III protein secretion/translocation system that is encoded by genes clustered in a 35.6 kb DNA segment, named the locus of enterocyte effacement (LEE). We...
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