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Evaluation of Oxidative DNA Damage in Human Sperm and Its Association with Male Infertility

12 Nov 1999

Abstract excerpt

Recently, there is increasing evidence suggesting that oxidative sperm DNA damage is closely associated with impaired sperm function and male infertility. 8-Hydroxydeoxyguanosine (8-OHdG) is considered to be a precise and sensitive biomarker of oxidative DNA damage. The present study was thus designed to evaluate the extent of oxidative DNA damage in sperm and its association with male infertility by assaying the...

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PMID: 10591610
DOI: 10.1002/j.1939-4640.1999.tb03376.x

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