Article
The dynamics of chromosome evolution in birds and mammals.
Nature - 25 Nov 1999
Burt D W, Bruley C, Dunn I C, Jones C T, Ramage A, Law A S, Morrice D R, Paton I R, Smith J, Windsor D, Sazanov A, Fries R, Waddington D
Abstract excerpt
Comparative mapping, which compares the location of homologous genes in different species, is a powerful tool for studying genome evolution. Comparative maps suggest that rates of chromosomal change in mammals can vary from one to ten rearrangements per million years. On the basis of these rates we would expect 84 to 600 conserved segments in a chicken comparison with human or mouse. Here we build comparative...
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