Article
Multilocus genotypes and DNA fingerprints Do not predict variation in azole resistance among clinical isolates of Candida albicans.
Antimicrobial agents and chemotherapy - 1 Dec 1999
Cowen L E, Sirjusingh C, Summerbell R C, Walmsley S, Richardson S, Kohn L M, Anderson J B
Abstract excerpt
If variation in azole resistance is due to inherent differences in strains of Candida albicans, as a predominantly clonal organism, then correlation between multilocus genotypes and drug resistance would be expected. A sample of 81 clinical isolates from patients infected with human immunodeficiency virus in Toronto, Canada, plus 3 reference isolates were genotyped at 16 loci, distributed on all linkage groups,...
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