Article
Increased Myogenic Potential and Fusion of Matrilysin-Expressing Myoblasts Transplanted in Mice
1 Sept 1999
Abstract excerpt
The success of myoblast transplantation in clinical trials has been limited in part by the low dispersion of grafted cells outside the injection site. Our research group previously reported that the culture of myoblasts with concanavalin A, a stimulator of metalloproteinase production, increased their migration. Several lines of evidence also suggested that muscle cell fusion involves metalloproteinase-sensitive...
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