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Article

Effect of mutations within the cys-rich region of potyvirus helper component-proteinase on self-interaction.

The Journal of general virology - 1 Nov 1999

Urcuqui-Inchima Silvio, Maia Ivan G, Drugeon Gabrièle, Haenni Anne-Lise, Bernardi Françoise

Abstract excerpt

The first approximately 60 amino acids of the N-terminal part of the potyvirus helper component-proteinase (HC-Pro) include highly conserved residues comprising a Cys-rich region. In the present study, the domain in Potato virus Y sufficient for self-interaction was mapped using the yeast two-hybrid system to the 83 N-terminal amino acids of HC-Pro. Mutations in the conserved His and two Cys residues within the...

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Source

Identifiers

PMID: 10580041
DOI: 10.1099/0022-1317-80-11-2809

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Research trail→

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Effect of mutations within the cys-rich region of potyvirus helper component-proteinase on self-interaction.PMID 10580041Read ↗

Mutations in the region encoding the central domain of helper component-proteinase (HC-Pro) eliminate potato virus X/potyviral synergism.Semantic proximity Read ↗

Structural characterization of HC-Pro, a plant virus multifunctional protein.Semantic proximity Read ↗

Molecular studies of the synergistic interactions between plum pox virus HC-Pro protein and potato virus X.Semantic proximity Read ↗

Comparative sequence of the helper component (HC) region of potato virus Y and a HC-defective strain, potato virus C.Semantic proximity Read ↗

Requirement for HC-Pro processing during genome amplification of tobacco etch potyvirus.Semantic proximity Read ↗

Mutational analysis of interaction between coat protein and helper component-proteinase of Soybean mosaic virus involved in aphid transmission.Semantic proximity Read ↗

Critical regions and residues for self-interaction of grapevine leafroll-associated virus 2 protein p24.Semantic proximity Read ↗

Development of an attenuated potato virus Y mutant carrying multiple mutations in helper-component protease for cross-protection.Semantic proximity Read ↗

The conserved FRNK box in HC-Pro, a plant viral suppressor of gene silencing, is required for small RNA binding and mediates symptom development.Semantic proximity Read ↗

Potyvirus helper component-proteinase and coat protein (CP) have coordinated functions in virus-host interactions and the same CP motif affects virus transmission and accumulation.Semantic proximity Read ↗

A mutation near the active site of S-RNase causes self-compatibility in S-RNase-based self-incompatible plants.Semantic proximity Read ↗

Mutations in the HC-Pro gene of zucchini yellow mosaic potyvirus: effects on aphid transmission and binding to purified virions.Semantic proximity Read ↗

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