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Article

A 28-kb deletion spanning D15S63 (PW71) in five families: a rare neutral variant?

American journal of human genetics - 1 Dec 1999

Buiting K, Dittrich B, Dworniczak B, Lerer I, Abeliovich D, Cottrell S, Temple I K, Harvey J F, Lich C, Gross S, Horsthemke B

Abstract excerpt

Methylation analysis with probe PW71 (D15S63) is an established procedure to test patients suspected of having Prader-Willi syndrome or Angelman syndrome. Using this test, we have identified a 28-kb deletion spanning D15S63 in five independent families. Sequence analysis revealed identical breakpoints in all the families. The haplotype data are compatible with a common ancestral origin of the deletion in at least...

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Identifiers

PMID: 10577912
DOI: 10.1086/302670
PMCID: PMC1288369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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